Publications scientifiques

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2021 BICKI®IL-7, optimized bifunctional anti PD-1/IL-7 drug, with good PK profile and preclinical anti-tumor efficacy: AACR 2021
2021 Agonist anti-ChemR23 mAb reduces tissue neutrophil accumulation and triggers chronic inflammation resolution: Science Advances
2020 Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance: Journal of Clinical Investigation
2020 Tissue-resident memory CD8 T-cell responses elicited by a single injection of a multi-target COVID-19 vaccine: BioRxiv
2019 IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease, JCI May 2019
2019 Early signs of activity of Tedopi (OSE2101), a multiple neoepitope vaccine, in a phase 3 trial in advanced lung cancer patients after failure to previous immune checkpoint inhibitors (ICI) Atalante 1 study trial: AACR 2019
2018 Full antagonist of the IL-7 receptor suppresses chronic inflammation in non-human primate models by controlling antigen-specific memory T cells: Cell Stress
2018 SIRPα/CD47 axis controls the maintenance of transplant tolerance sustained by myeloid‐derived suppressor cells: American Journal of Transplantation
2018 Vaccines as an Integral Component of Cancer Immunotherapy: JAMA
2018 IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates: Nature Communications
2018 Monotherapy with a SIRPα CKI leads to dramatic change in solid tumor microenvironment and prevents metastasis development: AACR 2018
2018 Selective SIRPa blockade potentiates human dendritic cell antigen cross-presentation and triggers memory T cell anti-tumor responses: AACR 2018
2018 CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates: Journal of Clinical Investigation
2017 Selective blockade of CD28 on human T cells facilitates regulation of alloimmune responses: Journal of Clinical Investigation
2017 CD28 Blockade Ex Vivo Induces Alloantigen-Specific Immune Tolerance but Preserves T-Cell Pathogen Reactivity: Frontiers in Immunology
2017 IL-7 pathway controls human T cell homing to the gut and culminates in inflammatory bowel disease mucosa: FOCIS 2017
2017 Interleukin-7 receptor pathway controls human T cell homing to the gut and predicts response to anti-TNFα therapy in IBD: AAI 2016
2017 Selective targeting of SIRP-alpha induces potent antitumor memory immune responses: AACR 2017
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