Publications scientifiques

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2018 Monotherapy with a SIRPα CKI leads to dramatic change in solid tumor microenvironment and prevents metastasis development: AACR 2018

2018 Selective SIRPa blockade potentiates human dendritic cell antigen cross-presentation and triggers memory T cell anti-tumor responses: AACR 2018

2018 CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates: Journal of Clinical Investigation

2017 Selective blockade of CD28 on human T cells facilitates regulation of alloimmune responses: Journal of Clinical Investigation

2017 CD28 Blockade Ex Vivo Induces Alloantigen-Specific Immune Tolerance but Preserves T-Cell Pathogen Reactivity: Frontiers in Immunology

2017 IL-7 pathway controls human T cell homing to the gut and culminates in inflammatory bowel disease mucosa: FOCIS 2017

2017 Interleukin-7 receptor pathway controls human T cell homing to the gut and predicts response to anti-TNFα therapy in IBD: AAI 2016

2017 Selective targeting of SIRP-alpha induces potent antitumor memory immune responses: AACR 2017

2017 Anti-CD28 Antibody and Belatacept Exert Differential Effects on Mechanisms of Renal Allograft Rejection: Journal of the American Society of Nephrology

2017 The role of IL-7 in Immunity and Cancer: Anticancer Research

2016 First-in-Human Study in Healthy Subjects with FR104, a Pegylated Monoclonal Antibody Fragment Antagonist of CD28: Journal of immunology

2016 The Present and Future of Inflammatory Bowel Disease Treatment: Advances in IBD

2016 Considerations for the combination of anticancer vaccines and immune checkpoint inhibitors: Expert Opin Biol Ther

2016 Control of immune tolerance by the SIRPα - CD47 pathway and Myeloid-Derived Suppressor Cells: EACR 2016

2016 Selective targeting of the SIRPα immune checkpoint, but not CD47, controls the polarization of macrophages: EACR 2016

2016 Dual targeting of adaptive and innate checkpoints induce potent memory anti-tumor response: EACR 2016

2016 Combination Cancer Therapies with Immune Checkpoint Blockade: Convergence on Interferon Signaling: Cell

2016 Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade: Science

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